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Modelling of human nonalcoholic fatty liver disease with hepatocyte like cells derived from pluripotent stem cells

N Graffmann, MA Kawala, S Ring, W Wruck, J Adjaye · Zeitschrift für Gastroenterologie · Ausgabe 12/2015

DOI 10.1055/s-0035-1568043

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Autor:innenN Graffmann, MA Kawala, S Ring, W Wruck, J Adjaye
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Nonalcoholic fatty liver disease (NAFLD) is an increasingly common diagnosis in the Western Hemisphere. It is defined by an accumulation of lipid droplets in more than 5% of hepatocytes. In the beginning the disease is rather benign, but later on patients develop steatohepatitis, cirrhosis and up to 27% of these patients end up with hepatocellular carcinoma. The molecular reasons of this disease are still questioned…

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N Graffmann, MA Kawala, S Ring, W Wruck, J Adjaye (2015) Modelling of human nonalcoholic fatty liver disease with hepatocyte like cells derived from pluripotent stem cells. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568043

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