CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The liver specific microRNA-122 modulates hepatic response to infection and inflammation by antagonizing YY1, FoxP3, Nfr1 and E2F4 molecular networks
DOI 10.1055/s-0035-1568052
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Paluschinski, D Häussinger, M Castoldi
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The liver specific microRNA miR-122 is essential for the maintenance of liver functionality. miR-122 deficient mice develop a pro-inflammatory phenotype in the liver, displaying an increased tendency in developing hepatocellular carcinoma (HCC). miR-122 transcription is regulated by Liver Enriched Transcription Factors (LETF). Transient inhibition of miR-122 activity results in the development of iron deficiency and…
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Zitierempfehlung
M Paluschinski, D Häussinger, M Castoldi (2015) The liver specific microRNA-122 modulates hepatic response to infection and inflammation by antagonizing YY1, FoxP3, Nfr1 and E2F4 molecular networks. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568052
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