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Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro

P Godoy, W Schmidt-Heck, G Campos, A Widera, R Stoeber, T Weiss, A Nussler, G Damm, B Küppers-Munther, DC Hay, JG Hengstler · Zeitschrift für Gastroenterologie · Ausgabe 12/2015

DOI 10.1055/s-0035-1568055

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Autor:innenP Godoy, W Schmidt-Heck, G Campos, A Widera, R Stoeber, T Weiss, A Nussler, G Damm, B Küppers-Munther, DC Hay, JG Hengstler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

The differentiation of embryonic stem cells (ESC) to hepatocytes offers the possibility of unlimited supply of human hepatocytes for cell therapy and biomedical research. However, current protocols achieve only a partial hepatocyte differentiation. This is largely due to our poor understanding of the transcriptional regulatory networks (TRN) governing stem cell and hepatocyte plasticity. Therefore, we performed a bi…

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Zitierempfehlung

P Godoy, W Schmidt-Heck, G Campos, A Widera, R Stoeber, T Weiss, A Nussler, G Damm, B Küppers-Munther, DC Hay, JG Hengstler (2015) Transcriptional regulatory networks governing stem cell differentiation into hepatocytes in vitro. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568055

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