CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1
DOI 10.1055/s-0035-1568071
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Weiler, F Pinna, T Lutz, T Wolf, S Roessler, S Wan, S Singer, M Knaub, J Marquardt, H Lang, JS Lee, P Schirmacher, V Kalinichenko, K Breuhahn
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The Hippo/YAP signaling pathway is an important regulator of cell proliferation and organ growth. YAP has been described as an oncogene, promoting hepatomegaly and the formation of hepatocellular carcinoma (HCC) (Zender et al. 2006). However, the precise downstream mechanisms of YAP-dependent tumorigenesis are only poorly understood. In this study we examined the role of YAP in the regulation of chromosomal instabil…
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Zitierempfehlung
S Weiler, F Pinna, T Lutz, T Wolf, S Roessler, S Wan, S Singer, M Knaub, J Marquardt, H Lang, JS Lee, P Schirmacher, V Kalinichenko, K Breuhahn (2015) Deregulation of the Hippo/YAP pathway drives chromosomal instability (CIN) in hepatocellular carcinoma by regulating the transcription factor FoxM1. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568071
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