CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease
DOI 10.1055/s-0035-1568074
Bibliografische Angaben
Nachweis in CareLit
Autor:innenYA Nevzorova, FJ Cubero, W Hu, F Hao, U Haas, P Ramadori, N Gassler, M Hoss, P Strnad, HW Zimmermann, F Tacke, C Trautwein, C Liedtke
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: Alcohol exposure may result in the overexpression of certain oncogenes in human cells thereby increasing the intracellular concentration of reactive oxygen species (ROS) and, thus, triggering initiation and progression of alcoholic liver disease (ALD). We previously showed that prolonged c-myc expression in hepatocytes leads to spontaneous fibrogenesis and end-stage high-latency tumor development.…
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Zitierempfehlung
YA Nevzorova, FJ Cubero, W Hu, F Hao, U Haas, P Ramadori, N Gassler, M Hoss, P Strnad, HW Zimmermann, F Tacke, C Trautwein, C Liedtke (2015) Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568074
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