CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Role of the bile acid receptor TGR5 (Gpbar-1) in gastrointestinal tumors
DOI 10.1055/s-0035-1568088
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Autor:innenK Deutschmann, M Reich, A Krieg, WT Knoefel, D Häussinger, V Keitel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The G-protein coupled bile acid receptor TGR5 (GPBAR1) is expressed in biliary epithelial cells of the liver as well as epithelial cell of the intestine. Receptor activation induces proliferation and anti-apoptotic effects in liver but in the intestine its function is relatively unclear. It was shown that secondary bile acids (BA) are involved in the development of different gastrointestinal (GI) maligna…
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Zitierempfehlung
K Deutschmann, M Reich, A Krieg, WT Knoefel, D Häussinger, V Keitel (2015) Role of the bile acid receptor TGR5 (Gpbar-1) in gastrointestinal tumors. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568088
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