CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Selective targeting of tumor-associated macrophages in hepatocellular carcinoma
DOI 10.1055/s-0035-1568090
Bibliografische Angaben
Nachweis in CareLit
Autor:innenB Kakoschky, C Schmithals, T Pleli, AA Talab, S Zeuzem, O Waidmann, HW Korf, A Weigert, A Piiper
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Hepatocellular carcinoma (HCC) is the third most frequent cause of cancer-related mortality worldwide showing a high resistance to therapy, sorafenib being the only drug prolonging life of patients for a few months. Tumor-associated macrophages (TAMs), which show alternative (M2) polarization and suppress immune function and promote tumor growth, angiogenesis and metastasis are valid therapeutic targets within the t…
Zitieren
Zitierempfehlung
B Kakoschky, C Schmithals, T Pleli, AA Talab, S Zeuzem, O Waidmann, HW Korf, A Weigert, A Piiper (2015) Selective targeting of tumor-associated macrophages in hepatocellular carcinoma. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568090
Mit CareLit weiterarbeiten