CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice
DOI 10.1055/s-0035-1568094
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Kah, S Koh, T Volz, L Allweiss, M Lütgehetmann, A Bertoletti, M Dandri
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Effective T cell responses are essential to resolve HBV infection. However, in chronic hepatitis B patients HBV-specific T cell responses appear severely impaired. Adoptive transfer of T cells engineered to express an HBV-specific T cell receptor (TCR) may contribute to viral load reduction and reconstitution of HBV-specific immune responses. Aim of the study was to assess the engraftment capabilities and antiviral…
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Zitierempfehlung
J Kah, S Koh, T Volz, L Allweiss, M Lütgehetmann, A Bertoletti, M Dandri (2015) Adaptive transfer of human T cells redirected against HBV results in reduced viral loads and induced immune responses in humanized mice. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568094
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