CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Amphipathic, nucleic acid-based polymers optimized to treat hepatitis B virus infection in patients do not harbour immune stimulatory properties in primary isolated blood or liver cells
DOI 10.1055/s-0035-1568098
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Nachweis in CareLit
Autor:innenR Broering, CI Real, M Werner, A Paul, G Gerken, A Vaillant, JF Schlaak
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Nucleic acid polymers (NAPs) are phosphorothioate oligonucleotides which interfere protein interactions involved in viral replication. This property is length dependent and sequence-independent. It has been demonstrated that NAPs are active against hepatitis B virus (HBV) where the antiviral mechanism is still being investigated. In this study, the immune stimulatory properties of NAPs optimized for the…
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Zitierempfehlung
R Broering, CI Real, M Werner, A Paul, G Gerken, A Vaillant, JF Schlaak (2015) Amphipathic, nucleic acid-based polymers optimized to treat hepatitis B virus infection in patients do not harbour immune stimulatory properties in primary isolated blood or liver cells. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568098
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