CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepatitis C virus inhibits IL-1β-induced IκBζ expression in a Calpain- and MK2-dependent manner resulting in LCN2 suppression
DOI 10.1055/s-0035-1568106
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Stindt, S Spitzley, R Bartenschlager, D Häussinger, JG Bode
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe12/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Hepatitis C virus (HCV) infection is a major cause of chronic liver disease worldwide, leading to end-stage cirrhosis and development of hepatocellular carcinoma. To achieve persistence, the virus has evolved several strategies to modulate the inflammatory response, cell proliferation, differentiation and prevent apoptosis. Here, we investigated the influence of HCV-mediated downregulation of the atypica…
Zitieren
Zitierempfehlung
S Stindt, S Spitzley, R Bartenschlager, D Häussinger, JG Bode (2015) Hepatitis C virus inhibits IL-1β-induced IκBζ expression in a Calpain- and MK2-dependent manner resulting in LCN2 suppression. Zeitschrift für Gastroenterologie (12). https://doi.org/10.1055/s-0035-1568106
Mit CareLit weiterarbeiten