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Exposure of airway epithelial cells to cigarette smoke extract causes the release of extracellular vesicles via thiol-reactive carbonyl compounds

B Benedikter, C Volgers, EFM Wouters, PHM Savelkoul, GRMM Haenen, G Rohde, AR Weseler, FRM Stassen · Pneumologie · Ausgabe 02/2016

DOI 10.1055/s-0036-1571987

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Autor:innenB Benedikter, C Volgers, EFM Wouters, PHM Savelkoul, GRMM Haenen, G Rohde, AR Weseler, FRM Stassen
ZeitschriftPneumologie
Ausgabe02/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Secreted extracellular vesicles (EVs) participate in multiple processes by transferring lipids, proteins and RNA between cells. Yet, their contribution to chronic inflammation in the lungs is largely unexplored. We determined if exposure of airway epithelial cells (AEC) to cigarette smoke extract (CSE) results in release of EVs. Using the CSE components H2O2 and acrolein, we determined the respective c…

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Zitierempfehlung

B Benedikter, C Volgers, EFM Wouters, PHM Savelkoul, GRMM Haenen, G Rohde, AR Weseler, FRM Stassen (2016) Exposure of airway epithelial cells to cigarette smoke extract causes the release of extracellular vesicles via thiol-reactive carbonyl compounds. Pneumologie (02). https://doi.org/10.1055/s-0036-1571987

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