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Effect of baseline FVC on decline in lung function with nintedanib in patients with idiopathic pulmonary fibrosis (IPF): results from the INPULSIS® trials

M Pfeifer, M Kolb, T Kimura, S Stowasser, C Hallmann, L Richeldi · Pneumologie · Ausgabe 02/2016

DOI 10.1055/s-0036-1572000

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Autor:innenM Pfeifer, M Kolb, T Kimura, S Stowasser, C Hallmann, L Richeldi
ZeitschriftPneumologie
Ausgabe02/2016
Jahrgang / SeitenNicht angegeben

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Background: The two replicate, randomised, placebo-controlled, 52-week INPULSIS® trials assessed the efficacy and safety of nintedanib 150 mg bid in patients with IPF. Patients with FVC ≥50% predicted were included. The primary endpoint, the annual rate of FVC decline, was significantly reduced in the nintedanib group compared with placebo in both trials, consistent with slowing of disease progression. Key secondary…

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M Pfeifer, M Kolb, T Kimura, S Stowasser, C Hallmann, L Richeldi (2016) Effect of baseline FVC on decline in lung function with nintedanib in patients with idiopathic pulmonary fibrosis (IPF): results from the INPULSIS® trials. Pneumologie (02). https://doi.org/10.1055/s-0036-1572000

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