CareLit · DOI-Nachweis · Pneumologie
Change of sildenafil plasma concentrations after transition from bosentan to macitentan in pulmonary arterial hypertension
DOI 10.1055/s-0036-1572030
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Autor:innenJ Ohnesorge, B Egenlauf, N Benjamin, C Fischer, Y Enderle, J Burhenne, A Huppertz, A Carls, WE Haefeli, E Grünig
ZeitschriftPneumologie
Ausgabe02/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Combination therapy of the phosphodiesterase-type 5 (PDE-5) inhibitor sildenafil and the endothelin receptor antagonist (ERA) bosentan may cause drug interactions in patients with pulmonary arterial hypertension (PAH). The objective of this study was to analyse plasma drug concentrations in PAH-patients during bosentan-sildenafil combination treatment and its changes after transition from bosentan to m…
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Zitierempfehlung
J Ohnesorge, B Egenlauf, N Benjamin, C Fischer, Y Enderle, J Burhenne, A Huppertz, A Carls, WE Haefeli, E Grünig (2016) Change of sildenafil plasma concentrations after transition from bosentan to macitentan in pulmonary arterial hypertension. Pneumologie (02). https://doi.org/10.1055/s-0036-1572030
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