CareLit · DOI-Nachweis · Pneumologie
The Tie2-Agonist Vasculotide Protects Lungs from Pneumonia-induced Barrier Disruption
DOI 10.1055/s-0036-1572079
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Autor:innenB Gutbier, X Jiang, C Ehrler, TJ Mitchell, N Weissmann, P Van Slyke, DJ Dumont, N Suttorp, M Witzenrath
ZeitschriftPneumologie
Ausgabe02/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: In pneumonia, pathogen-host interaction evokes inflammation and disruption of pulmonary endothelial barrier integrity resulting in acute lung injury despite antibiotic therapy. Treatment of acute lung injury is mainly supportive, since key elements of inflammation-induced barrier disruption remain undetermined. The angiopoietins (Ang) -1 and -2 and their receptor Tie2 are involved in the regulation of…
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Zitierempfehlung
B Gutbier, X Jiang, C Ehrler, TJ Mitchell, N Weissmann, P Van Slyke, DJ Dumont, N Suttorp, M Witzenrath (2016) The Tie2-Agonist Vasculotide Protects Lungs from Pneumonia-induced Barrier Disruption. Pneumologie (02). https://doi.org/10.1055/s-0036-1572079
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