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Interferons suppress IL-1beta dependent GM-CSF in post-influenza pneumococcal infection of human lungs

K Zscheppang, J Berg, D Fatykhova, M Tönnies, TT Bauer, P Schneider, J Neudecker, J Rückert, S Eggeling, M Schimek, A Gruber, N Suttorp, S Hippenstiel, AC Hocke · Pneumologie · Ausgabe 02/2016

DOI 10.1055/s-0036-1572222

Bibliografische Angaben

Nachweis in CareLit

Autor:innenK Zscheppang, J Berg, D Fatykhova, M Tönnies, TT Bauer, P Schneider, J Neudecker, J Rückert, S Eggeling, M Schimek, A Gruber, N Suttorp, S Hippenstiel, AC Hocke
ZeitschriftPneumologie
Ausgabe02/2016
Jahrgang / SeitenNicht angegeben

Kernaussage aus der Literatur

Abstract-Vorschau

The severity and lethality in influenza A virus (IAV) infections is frequently aggravated by secondary bacterial pneumonia. However, mechanisms in human lung tissue provoking this increase in fatality are unknown. We established a human lung ex vivo co-infection model to investigate innate immune related mechanisms contributing to the susceptibility of secondary pneumococcal pneumonia. We observed induction of type…

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Zitierempfehlung

K Zscheppang, J Berg, D Fatykhova, M Tönnies, TT Bauer, P Schneider, J Neudecker, J Rückert, S Eggeling, M Schimek, A Gruber, N Suttorp, S Hippenstiel, AC Hocke (2016) Interferons suppress IL-1beta dependent GM-CSF in post-influenza pneumococcal infection of human lungs. Pneumologie (02). https://doi.org/10.1055/s-0036-1572222

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