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The role of cytochrome c oxidase subunit 4 isoform 2 (Cox4i2) in chronic hypoxia induced pulmonary hypertension

F Jonas, C Veith-Berger, S Kraut, K Quanz, M Gierhardt, W Seeger, L Grossman, M Hüttemann, N Weissmann, N Sommer · Pneumologie · Ausgabe 02/2016

DOI 10.1055/s-0036-1572296

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Autor:innenF Jonas, C Veith-Berger, S Kraut, K Quanz, M Gierhardt, W Seeger, L Grossman, M Hüttemann, N Weissmann, N Sommer
ZeitschriftPneumologie
Ausgabe02/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Rationale: Exposure of the pulmonary vasculature to chronic hypoxia results in pulmonary vascular remodeling and development of pulmonary hypertension (PH) ultimately leading to right heart failure and death. Mitochondria have been suggested to be involved in proliferation of pulmonary arterial smooth muscle cells (PASMC) underlying pulmonary vascular remodeling. We thus aimed to investigate the role of the lung-spe…

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Zitierempfehlung

F Jonas, C Veith-Berger, S Kraut, K Quanz, M Gierhardt, W Seeger, L Grossman, M Hüttemann, N Weissmann, N Sommer (2016) The role of cytochrome c oxidase subunit 4 isoform 2 (Cox4i2) in chronic hypoxia induced pulmonary hypertension. Pneumologie (02). https://doi.org/10.1055/s-0036-1572296

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