CareLit · DOI-Nachweis · Pneumologie
IL-37 ameliorates experimental asthma via a mechanism that is independent from IL-18 signaling
DOI 10.1055/s-0036-1572306
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Schröder, L Lunding, S Webering, C Vock, D Raedler, B Schaub, H Fehrenbach, M Wegmann
ZeitschriftPneumologie
Ausgabe02/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Study objectives: IL-37 has been described as a negative regulator of innate immunity. Production of IL-37 is impaired in allergic asthmatics suggesting a role for IL-37 in asthma pathogenesis. We could demonstrate that IL-37 ameliorates experimental asthma via a mechanism that requires IL-18Rα and SIGIRR. This study is aimed to further clarify, how these effects on asthma pathogenesis are mediated. Methods: Experim…
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Zitierempfehlung
A Schröder, L Lunding, S Webering, C Vock, D Raedler, B Schaub, H Fehrenbach, M Wegmann (2016) IL-37 ameliorates experimental asthma via a mechanism that is independent from IL-18 signaling. Pneumologie (02). https://doi.org/10.1055/s-0036-1572306
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