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Hypothalamic inflammation in humans is not reversed by a profound weight loss and an improved insulin sensitivity due to bariatric surgery

C Kreutzer, S Peters, DM Schulte, K Türk, S Wolff, A Rohr, T Kerby, C Riedel, T van Eimeren, S Schreiber, M Laudes · Diabetologie und Stoffwechsel · Ausgabe 04/2016

DOI 10.1055/s-0036-1580757

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Autor:innenC Kreutzer, S Peters, DM Schulte, K Türk, S Wolff, A Rohr, T Kerby, C Riedel, T van Eimeren, S Schreiber, M Laudes
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: Obesity is associated with hypothalamic inflammation (HI) in animal models. While MRI studies in humans also found an increased intensity in the MBH in obese subjects it remains unclear (1) if HI causes neuronal death and (2) if HI reverses during weight loss. Patients and methods: n = 50 obese subjects and n = 50 age- and sex-matched controls where examined. MRI scans including spectroscopy were perfo…

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C Kreutzer, S Peters, DM Schulte, K Türk, S Wolff, A Rohr, T Kerby, C Riedel, T van Eimeren, S Schreiber, M Laudes (2016) Hypothalamic inflammation in humans is not reversed by a profound weight loss and an improved insulin sensitivity due to bariatric surgery. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580757

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