CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Protective function of ELMO1 in renal development under diabetic conditions within zebrafish and in human diabetic nephropathy
DOI 10.1055/s-0036-1580769
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Sharma, K Heckler, S Stoll, JL Hillebrands, K Kynast, E Herpel, S Porubsky, PP Nawroth, J Kroll
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: Engulfment and cell motility 1 (ELMO1) protein functions as a guanine exchange factor for Rac1 and protects endothelial cells from apoptosis. GWAS data suggests that polymorphisms in different regions of human ELMO1 acts as a contributing factor for the development of diabetic nephropathy (DN). Thus, this study aimed to identify the role played by ELMO1 in renal development in zebrafish, under d…
Zitieren
Zitierempfehlung
K Sharma, K Heckler, S Stoll, JL Hillebrands, K Kynast, E Herpel, S Porubsky, PP Nawroth, J Kroll (2016) Protective function of ELMO1 in renal development under diabetic conditions within zebrafish and in human diabetic nephropathy. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580769
Mit CareLit weiterarbeiten