CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Nicotinamide N-methyltransferase (NNMT) regulates insulin sensitivity differentially in white and brown adipocytes
DOI 10.1055/s-0036-1580809
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Nachweis in CareLit
Autor:innenB Zapp, NA Kraus, B Rudolphi, BJ Kraus, A Sauer, J Klein, C Wanner, D Kraus
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Nicotinamide N-methyltransferase (NNMT) is a novel regulator of energy homeostasis in adipose tissue. NNMT expression is increased in obesity. NNMT knockdown prevents from obesity. Mice lacking glucose transporter 4 (Glut4) in adipose tissue are insulin resistant and overexpress NNMT in fat. Fat-specific Glut4 transgenic mice are insulin hypersensitive and have low NNMT expression. Aim: In the present st…
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Zitierempfehlung
B Zapp, NA Kraus, B Rudolphi, BJ Kraus, A Sauer, J Klein, C Wanner, D Kraus (2016) Nicotinamide N-methyltransferase (NNMT) regulates insulin sensitivity differentially in white and brown adipocytes. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580809
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