CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Tissue distribution of nicotinamide N-methyltransferase activity in lean and in diet-induced obese mice
DOI 10.1055/s-0036-1580822
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Nachweis in CareLit
Autor:innenB Rudolphi, A Sauer, B Zapp, NA Kraus, C Wanner, D Kraus
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Nicotinamide N-methyltransferase (NNMT) is a novel regulator of energy metabolism in adipose tissue. NNMT expression in adipose tissue is increased in obesity. Knockdown protects mice from obesity. It is unknown however whether NNMT enzyme activity, rather than expression, is increased in obesity, and how it is distributed between tissues. Aim: We aimed to develop a non-radioactive NNMT activity assay in…
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Zitierempfehlung
B Rudolphi, A Sauer, B Zapp, NA Kraus, C Wanner, D Kraus (2016) Tissue distribution of nicotinamide N-methyltransferase activity in lean and in diet-induced obese mice. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580822
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