CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Clodronate treatment leads to microglial activation in degenerative retinopathy
DOI 10.1055/s-0036-1580829
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Autor:innenS Riemann, M Kolibabka, N Gretz, S Hoffmann, S Busch, HP Hammes
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Inflammation and glial activation can change the course of diabetic retinopathy (DR). The polycystic-kidney-disease (PKD)-rat shows a retinal phenotype similar to DR in which CD74 serves as a microglial activation marker. Our aim was to clarify the function of CD74+-microglia. PKD-rats were intravitreally injected with clodronate-coated-liposomes at 4 and 8 weeks of age and terminated at 12 weeks. Clodronate-injecte…
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Zitierempfehlung
S Riemann, M Kolibabka, N Gretz, S Hoffmann, S Busch, HP Hammes (2016) Clodronate treatment leads to microglial activation in degenerative retinopathy. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580829
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