CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Insulin granule mobility, cytosolic calcium concentration, and stimulated insulin secretion in MIN6 cells and beta cells: differences and similarities
DOI 10.1055/s-0036-1580890
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Autor:innenD Brüning, K Reckers, M Matz, K Baumann, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background and aims: The conventional view that insulin granules are sequentially recruited to release insulin has been superseded by newer, more complex models, resulting from TIRF imaging. Here, we compared insulin secretion, cytosolic Ca2+ concentration ([Ca2+]i) and granule mobility in MIN6 cells and in primary mouse beta cells. Methods: Insulin secretion was measured in perifused MIN6 pseudo-islets or cultured…
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Zitierempfehlung
D Brüning, K Reckers, M Matz, K Baumann, I Rustenbeck (2016) Insulin granule mobility, cytosolic calcium concentration, and stimulated insulin secretion in MIN6 cells and beta cells: differences and similarities. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580890
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