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Cation channels of the TRPC family contribute to development of nephropathy and retinopathy in the STZ model

D Schumacher, C Matka, R Sachdeva, N Dietrich, A Schlotterer, I Mathar, S Homberg, U Kriebs, P Stettner, PP Nawroth, HJ Gröne, HP Hammes, T Fleming, M Freichel · Diabetologie und Stoffwechsel · Ausgabe 04/2016

DOI 10.1055/s-0036-1580892

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Autor:innenD Schumacher, C Matka, R Sachdeva, N Dietrich, A Schlotterer, I Mathar, S Homberg, U Kriebs, P Stettner, PP Nawroth, HJ Gröne, HP Hammes, T Fleming, M Freichel
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

The pathogenesis of hyperglycemia-dependent diabetic longterm complications involves the accumulation of reactive metabolites which were recently shown to affect cation channels such as Nav1.8 and TRPA1 channels as targets and essential effector molecules in signaling pathways involved in the disease process. Likewise, other members of the TRP cation channel family including members of TRPC and TRPM family are regul…

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D Schumacher, C Matka, R Sachdeva, N Dietrich, A Schlotterer, I Mathar, S Homberg, U Kriebs, P Stettner, PP Nawroth, HJ Gröne, HP Hammes, T Fleming, M Freichel (2016) Cation channels of the TRPC family contribute to development of nephropathy and retinopathy in the STZ model. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580892

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