CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
The metabolic amplification of insulin secretion is strongly affected by cell culture
DOI 10.1055/s-0036-1580895
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Nachweis in CareLit
Autor:innenM Morsi, T Schulze, K Reckers, N Görgler, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: Metabolic amplification of insulin secretion is still poorly understood in spite of considerable research efforts. Here, we have tested the hypothesis that at least part of the conflicting results is due to different cellular models. Methods: Freshly isolated or cultured (24 to 48h in RPMI1640) mouse islets were used to measure insulin secretion by perifusion and ELISA of the fractionated efflux…
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Zitierempfehlung
M Morsi, T Schulze, K Reckers, N Görgler, I Rustenbeck (2016) The metabolic amplification of insulin secretion is strongly affected by cell culture. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580895
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