CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Mefloquine, a useful tool to investigate hemichannel function in pancreatic beta cells?
DOI 10.1055/s-0036-1580897
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Nachweis in CareLit
Autor:innenN Görgler, A Welling, I Rustenbeck
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: It is generally assumed that potassium depolarization leads to the same depolarization-induced insulin secretion as the closure of KATP channels. We have found, however, that it leads to a strong further increase when KATP channels were blocked by tolbutamide. This effect involves increases of the cytosolic Ca2+ concentration. It is unclear however, whether the Ca2+ influx occurs via voltage-dep…
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Zitierempfehlung
N Görgler, A Welling, I Rustenbeck (2016) Mefloquine, a useful tool to investigate hemichannel function in pancreatic beta cells?. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580897
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