CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Slc13a5/mINDY inhibition prevents diet-induced non-alcoholic fatty liver disease in mice and rats
DOI 10.1055/s-0036-1580910
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Brachs, AF Winkel, H Tang, AL Birkenfeld, H Glombik, A Dudda, B Brunner, K Jahn-Hofmann, D Margerie, AW Herling, H Ruetten, D Schmoll, J Spranger
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Aims: Non-alcoholic fatty liver disease (NAFLD) is a world-wide health concern and risk factor for cardio-metabolic diseases. Citrate uptake modifies intracellular hepatic energy metabolism and is controlled by the conserved sodium-dicarboxylate cotransporter solute carrier family 13 member 5 (SLC13A5, mINDY). Genetic deletion in mice protected from diet-induced adiposity and insulin resistance. Here, we investigate…
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Zitierempfehlung
S Brachs, AF Winkel, H Tang, AL Birkenfeld, H Glombik, A Dudda, B Brunner, K Jahn-Hofmann, D Margerie, AW Herling, H Ruetten, D Schmoll, J Spranger (2016) Slc13a5/mINDY inhibition prevents diet-induced non-alcoholic fatty liver disease in mice and rats. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580910
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