CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Differences on hepatic Igfbp2 methylation and expression occur before the onset of fatty liver disease
DOI 10.1055/s-0036-1580911
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Autor:innenA Kammel, S Saussenthaler, M Jähnert, W Jonas, HG Joost, A Schürmann, RW Schwenk
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe04/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: NAFLD patients exhibit decreased hepatic Insulin-like growth factor binding protein-2 (IGFBP2) expression associated with decreased DNA methylation1. Transcriptome analysis of livers from adiposity-susceptible (responder) C57BL/6J mice showed also decreased expression levels of hepatic Igfbp2 compared to adiposity-resistant (non-responder) mice. The aim of this study was to test if hepatic DNA methylatio…
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Zitierempfehlung
A Kammel, S Saussenthaler, M Jähnert, W Jonas, HG Joost, A Schürmann, RW Schwenk (2016) Differences on hepatic Igfbp2 methylation and expression occur before the onset of fatty liver disease. Diabetologie und Stoffwechsel (04). https://doi.org/10.1055/s-0036-1580911
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