CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Vitamin D3 improves liver histology and hepatic gene expression in a murine obesity/NASH model independent of intestinal FGF15
DOI 10.1055/s-0036-1582064
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Jahn, D Dorbath, S Kircher, HM Hermanns, A Geier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background and aims: 25-OH vitamin D3 (VD3) serum levels negatively correlate with obesity and NAFLD in humans, the mechanisms linking low VD3 status to disease progression are, however, not fully understood. The gut-derived hormone FGF19 (FGF15 in mice) impacts on liver metabolism and induces various beneficial effects that may help to treat obesity and NAFLD. Previous data has shown that Fgf15 transcription in mic…
Zitieren
Zitierempfehlung
D Jahn, D Dorbath, S Kircher, HM Hermanns, A Geier (2016) Vitamin D3 improves liver histology and hepatic gene expression in a murine obesity/NASH model independent of intestinal FGF15. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0036-1582064
Mit CareLit weiterarbeiten