CareLit · DOI-Nachweis · Klinische Pädiatrie
Effective targeting of Acute Lymphoblastic Leukemia (ALL) by CD70 directed immunotherapy
DOI 10.1055/s-0036-1582481
Bibliografische Angaben
Nachweis in CareLit
Autor:innenQ Sun, KM Debatin, LH Meyer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Despite good overall outcome of children with ALL, relapse is associated with poor prognosis emphasizing the need for novel therapies. Previously, we observed high CD70 transcript levels in high risk ALL. Here, we address CD70 as target for immunotherapy. Methods: Analysis of CD70 surface expression on ALL cells, evaluation of CD70-directed immunotherapy in different xenograft mouse modes. Results: Hig…
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Zitierempfehlung
Q Sun, KM Debatin, LH Meyer (2016) Effective targeting of Acute Lymphoblastic Leukemia (ALL) by CD70 directed immunotherapy. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0036-1582481
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