CareLit · DOI-Nachweis · Klinische Pädiatrie
Comparison of different tag purification approaches to create GATA1-/GATA1 s-centered protein interaction networks
DOI 10.1055/s-0036-1582482
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Mahnken, JH Klusmann
ZeitschriftKlinische Pädiatrie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Children with trisomy 21 (Down syndrome, DS) are predisposed to develop acute megakaryoblastic leukemia (DS-AMKL). Mutations in the transcription factor GATA1 and translation of the resulting truncated protein (GATA1 s) are both essential and sufficient to cause transient abnormal myelopoiesis (TAM) in synergy with trisomy 21. However, the molecular interplay between GATA1 s and trisomy 21 remains inco…
Zitieren
Zitierempfehlung
A Mahnken, JH Klusmann (2016) Comparison of different tag purification approaches to create GATA1-/GATA1 s-centered protein interaction networks. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0036-1582482
Mit CareLit weiterarbeiten