CareLit · DOI-Nachweis · Klinische Pädiatrie
CRISPRi/a screening to identify functional long non-coding RNAs in pediatric acute myeloid leukemia
DOI 10.1055/s-0036-1582485
Bibliografische Angaben
Nachweis in CareLit
Autor:innenM Ng, L Santer, S Emmrich, A Schwarzer, D Reinhardt, JH Klusmann
ZeitschriftKlinische Pädiatrie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Long non-coding RNAs (lncRNAs) recently emerged as developmental stage and cell context-specific regulators of gene expression, posing a novel window for targeted therapies in pediatric acute myeloid leukemias (AMLs). Results: We established a microarray-based lncRNA expression atlas for the hematopoietic system including 46 pediatric AML patient samples, and discovered a shared lncRNA signature specif…
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Zitierempfehlung
M Ng, L Santer, S Emmrich, A Schwarzer, D Reinhardt, JH Klusmann (2016) CRISPRi/a screening to identify functional long non-coding RNAs in pediatric acute myeloid leukemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0036-1582485
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