CareLit · DOI-Nachweis · Klinische Pädiatrie
Stem cell-enriched long non-coding RNA HOXA-AS4 contributes to the pathogenesis of MLL-rearranged AML
DOI 10.1055/s-0036-1582487
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Al-Kershi, S Emmrich, C Reimer, JH Klusmann
ZeitschriftKlinische Pädiatrie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Homeobox (HOX) genes play an essential role during embryogenesis and hematopoiesis. Their dysregulation is crucial for MLL-induced leukemogenesis. To date, the contribution of long non-coding RNAs (lncRNAs) located within the HOXA-cluster to the pathogenesis of AML remains unknown. Results: Our microarray lncRNA expression atlas for the hematopoietic system, including 46 pediatric AML patient samples,…
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Zitierempfehlung
S Al-Kershi, S Emmrich, C Reimer, JH Klusmann (2016) Stem cell-enriched long non-coding RNA HOXA-AS4 contributes to the pathogenesis of MLL-rearranged AML. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0036-1582487
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