CareLit · DOI-Nachweis · Klinische Pädiatrie
Spatial diversity of abundant and equipotent founder clones in acute lymphoblastic leukaemia
DOI 10.1055/s-0036-1582488
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Autor:innenAK Elder, O Heidenreich, HJ Vormoor
ZeitschriftKlinische Pädiatrie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: In recent years there has been increasing focus on the extent to which intra-tumour heterogeneity influences the development and evolution of cancer. Although there is evidence that ALL samples consist of a genetically heterogeneous subclonal architecture, it is unclear how individual clones differ at the functional level. Methods: We used a cellular barcoding approach to label individual clones with h…
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Zitierempfehlung
AK Elder, O Heidenreich, HJ Vormoor (2016) Spatial diversity of abundant and equipotent founder clones in acute lymphoblastic leukaemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0036-1582488
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