CareLit · DOI-Nachweis · Klinische Pädiatrie
Redeployed drug inducing MLL fusion degradation
DOI 10.1055/s-0036-1582491
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Cantilena, O Heidenreich, JH Klussman, O Williams, J de Boer
ZeitschriftKlinische Pädiatrie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Acute leukemias in infants are quite rare but generate a great interest due to the aggressive clinical features. The survival rate for these infants is less than 50%. The vast majority of infant acute leukemias are characterized cytogenetically by balanced chromosomal translocations involving the mixed lineage leukemia (MLL) gene. Leukemic therapies that degrade the driver oncogene are associated with…
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Zitierempfehlung
S Cantilena, O Heidenreich, JH Klussman, O Williams, J de Boer (2016) Redeployed drug inducing MLL fusion degradation. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0036-1582491
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