CareLit · DOI-Nachweis · Klinische Pädiatrie
BCP-ALL blasts are not dependent on CD19 expression for leukaemic maintenance
DOI 10.1055/s-0036-1582497
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Weiland, D Pal, M Case, J Irving, F Ponthan, S Koschmieder, O Heidenreich, A von Stackelberg, C Eckert, J Vormoor, A Elder
ZeitschriftKlinische Pädiatrie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: The B-lymphocyte surface marker CD19 is the focus of attention for the development of immunotherapies due to its high expression on leukemic blasts and B-lineage specificity. The monoclonal antibody blinatumomab and chimeric antigen receptor modified T-cells targeting CD19 have shown early promise in clinical trials in the treatment of B cell precursor acute lymphoblastic leukaemia (BCP-ALL). However,…
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Zitierempfehlung
J Weiland, D Pal, M Case, J Irving, F Ponthan, S Koschmieder, O Heidenreich, A von Stackelberg, C Eckert, J Vormoor, A Elder (2016) BCP-ALL blasts are not dependent on CD19 expression for leukaemic maintenance. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0036-1582497
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