CareLit · DOI-Nachweis · Klinische Pädiatrie
Antileukemic activity of the azacitidine in a xenograft model of juvenile myelomonocytic leukemia
DOI 10.1055/s-0036-1582499
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Nachweis in CareLit
Autor:innenCF Krombholz, S Fluhr, CM Niemeyer, C Flotho, M Erlacher
ZeitschriftKlinische Pädiatrie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Juvenile myelomonocytic leukemia (JMML) is an aggressive myeloproliferative disorder of early childhood. Patients present with hepatosplenomegaly, lymphadenopathy and skin rash, and peripheral blood analysis reveals monocytosis and the presence of myeloid precursors. Clinical signs are caused by organ infiltration of proliferating monocytes and granulocytes. JMML cells are characterized by a deregulate…
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Zitierempfehlung
CF Krombholz, S Fluhr, CM Niemeyer, C Flotho, M Erlacher (2016) Antileukemic activity of the azacitidine in a xenograft model of juvenile myelomonocytic leukemia. Klinische Pädiatrie (05). https://doi.org/10.1055/s-0036-1582499
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