CareLit · DOI-Nachweis · Aktuelle Ernährungsmedizin
Drug-Food Interactions induced by proton-pump inhibitors: decreased bioavailability of transition metals due to pH-dependent worsening of aquo-complexes' solubility
DOI 10.1055/s-0036-1583868
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJenzer, H.; Marty, I.; Ruch, L.; Scheidegger-Balmer, F.; Sadeghi, L.
ZeitschriftAktuelle Ernährungsmedizin
Ausgabe3/2016
Jahrgang / SeitenJg. 19 · S. 1 bis 1
Kernaussage aus der Literatur
Abstract-Vorschau
Purpose: Malabsorption of micronutrients is an adverse effect of proton pump inhibitors (PPIs). This work elucidates worsening solubility of metal aquo-complexes when changing gastrointestinal pH from 2.0 (men) or 2.5 (women) to permanently more than 4.0. Methods: A simple model of solubility of trace metal ions at GI tube-like pH was validated. Mixtures of 0.5% FeCl3 or CuSO4 with or w/o 1% ascorbic acid (to stabil…
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Zitierempfehlung
Jenzer, H.; Marty, I.; Ruch, L.; Scheidegger-Balmer, F.; Sadeghi, L (2016) Drug-Food Interactions induced by proton-pump inhibitors: decreased bioavailability of transition metals due to pH-dependent worsening of aquo-complexes' solubility. Aktuelle Ernährungsmedizin, 19 (3), 1 bis 1. https://doi.org/10.1055/s-0036-1583868
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