CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Bacterial translocation into the mucus of crypts is associated with proximal colonic tumorigenesis in IL-10-/-xMSH2loxP/loxP Vill-cre (DKO) mice
DOI 10.1055/s-0036-1584022
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Nachweis in CareLit
Autor:innenM Lang, A Rozalska, D Berry, A Riva, C Gasche
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Intestinal dysbiosis is associated with inflammatory bowel disease and colorectal cancer. In humans, specifically right-sided tumors are associated with bacterial biofilms and invasive bacteria. Typically, Lynch syndrome patients have right-sided tumors, which appear mucinous with a high inflammatory infiltrate. Herein we cross-bred MSH2loxP/loxP Vill-cre mice into the IL-10-/- background to study the im…
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Zitierempfehlung
M Lang, A Rozalska, D Berry, A Riva, C Gasche (2016) Bacterial translocation into the mucus of crypts is associated with proximal colonic tumorigenesis in IL-10-/-xMSH2loxP/loxP Vill-cre (DKO) mice. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0036-1584022
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