CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic Schistosomiasis
DOI 10.1055/s-0036-1584053
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Nachweis in CareLit
Autor:innenM Sombetzki, CD Fuchs, CH Österreicher, EC Reisinger, M Trauner
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background & Aims: Intrahepatic granuloma formation and fibrosis characterize the pathological features of Schistosoma mansoni (S.m.) infection. Based on previously observed substantial anti-fibrotic effects of 24-nor-ursodeoxycholic acid (norUDCA) in Abcb4/Mdr2-/-mice with cholestatic liver injury and biliary fibrosis, we hypothesized that norUDCA improves inflammation-driven liver fibrosis in S.m. infection. Metho…
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Zitierempfehlung
M Sombetzki, CD Fuchs, CH Österreicher, EC Reisinger, M Trauner (2016) 24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic Schistosomiasis. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0036-1584053
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