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Pruritus during anti-HCV treatment with PTV/r/OBV+/-DSV is associated with increased bile acid levels.

R Stauber, G Fauler, F Rainer, A Posch, A Streit, W Spindelböck, V Stadlbauer, H Mangge · Zeitschrift für Gastroenterologie · Ausgabe 05/2016

DOI 10.1055/s-0036-1584070

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Autor:innenR Stauber, G Fauler, F Rainer, A Posch, A Streit, W Spindelböck, V Stadlbauer, H Mangge
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2016
Jahrgang / SeitenNicht angegeben

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Introduction: Interferon-free anti-HCV treatment with paritaprevir/ritonavir + ombitasvir +/- dasabuvir (PTV/r/OBV+/-DSV) is highly effective and well-tolerated with only minimal side effects. However, pruritus has been observed in phase III trials in up to 20% of patients and seems to be unique for this DAA combination. The aim of this study was to investigate the effect of PTV/r/OBV+/-DSV on bile acid levels and t…

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R Stauber, G Fauler, F Rainer, A Posch, A Streit, W Spindelböck, V Stadlbauer, H Mangge (2016) Pruritus during anti-HCV treatment with PTV/r/OBV+/-DSV is associated with increased bile acid levels. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0036-1584070

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