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Towards a multi-organ-chip platform combining human liver, pancreatic islets, skeletal muscle and kidney equivalents to study metabolic diseases

S Bauer, C Magauer, I Maschmeyer, C Drewell, A Lorenz, R Lauster, U Marx · Diabetologie und Stoffwechsel · Ausgabe 06/2016

DOI 10.1055/s-0036-1584105

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Autor:innenS Bauer, C Magauer, I Maschmeyer, C Drewell, A Lorenz, R Lauster, U Marx
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe06/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: In vivo experiments for the study of metabolic diseases are crucial, however limited due to phylogenetic differences between humans and animals. Here, an approach to systemically combine several human organ models to study pathogenesis and therapeutic intervention in metabolic diseases is shown. Methods: At the size of a microscopic glass slide, the multi-organ-chip consists of two independent microfluid…

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S Bauer, C Magauer, I Maschmeyer, C Drewell, A Lorenz, R Lauster, U Marx (2016) Towards a multi-organ-chip platform combining human liver, pancreatic islets, skeletal muscle and kidney equivalents to study metabolic diseases. Diabetologie und Stoffwechsel (06). https://doi.org/10.1055/s-0036-1584105

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