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Adverse Reactions against Biologicals – Identification and Characterization of Immunogenic Epitopes and Potential Biomarkers

A Homann, S Minge, N Röckendorf, A Kromminga, A Frey, T Platts-Mills, U Jappe · Pneumologie · Ausgabe 07/2016

DOI 10.1055/s-0036-1584604

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Autor:innenA Homann, S Minge, N Röckendorf, A Kromminga, A Frey, T Platts-Mills, U Jappe
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben

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Background: Today there is an increase in the indication for biologicals for the treatment of various inflammatory diseases. For example, TNF-alpha blockers are used for the treatment of rheumatic disease, which also affects the lung by pulmonary hypertension and fibrosis. However, during treatment, several clinically relevant side effects occur: loss of drug efficacy, hypersensitivity and anaphylactic reactions whi…

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A Homann, S Minge, N Röckendorf, A Kromminga, A Frey, T Platts-Mills, U Jappe (2016) Adverse Reactions against Biologicals – Identification and Characterization of Immunogenic Epitopes and Potential Biomarkers. Pneumologie (07). https://doi.org/10.1055/s-0036-1584604

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