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Macrophages render alveolar epithelial cells hypo-responsive to Legionella pneumophila

C Schulz, X Lai, AL Jung, A Sittka-Stark, C Herkt, W Bertrams, J Vera, B Schmeck · Pneumologie · Ausgabe 07/2016

DOI 10.1055/s-0036-1584613

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Autor:innenC Schulz, X Lai, AL Jung, A Sittka-Stark, C Herkt, W Bertrams, J Vera, B Schmeck
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Pneumonia is a leading cause of mortality worldwide. To secure organ function, pulmonary innate immune response has to be tightly regulated. Here, we analyze whether macrophages influence immune reactivity of type II alveolar epithelial cells during infection with an intracellular bacterial pathogen. For this purpose, human macrophage-like differentiated THP-1 cells were co-cultured with human alveolar epithelial A5…

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C Schulz, X Lai, AL Jung, A Sittka-Stark, C Herkt, W Bertrams, J Vera, B Schmeck (2016) Macrophages render alveolar epithelial cells hypo-responsive to Legionella pneumophila. Pneumologie (07). https://doi.org/10.1055/s-0036-1584613

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