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Differentially expressed miRNAs after Legionella pneumophila infection of human macrophages

C Herkt, A Marsico, W Bertrams, W Chen, S Schmeck, A Sittka-Stark · Pneumologie · Ausgabe 07/2016

DOI 10.1055/s-0036-1584614

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Autor:innenC Herkt, A Marsico, W Bertrams, W Chen, S Schmeck, A Sittka-Stark
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben

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Introduction: Legionella pneumophila (L. p.) is a common cause of severe community-acquired pneumonia. This pathogen replicates primarily within alveolar macrophages and manipulates the host reaction by interfering with intracellular signaling pathways and gene transcription to support its own replication. MicroRNAs (miRNAs) have emerged as critical regulators of mRNAs and are also directly involved in the innate im…

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C Herkt, A Marsico, W Bertrams, W Chen, S Schmeck, A Sittka-Stark (2016) Differentially expressed miRNAs after Legionella pneumophila infection of human macrophages. Pneumologie (07). https://doi.org/10.1055/s-0036-1584614

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