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Immunomodulatory role of IL-37 in asthma pathogenesis

A Schröder, L Lunding, S Webering, C Vock, D Raedler, B Schaub, H Fehrenbach, M Wegmann · Pneumologie · Ausgabe 07/2016

DOI 10.1055/s-0036-1584619

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Autor:innenA Schröder, L Lunding, S Webering, C Vock, D Raedler, B Schaub, H Fehrenbach, M Wegmann
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Introduction: The recently identified cytokine IL-37 has been described as a negative regulator of innate immunity. Since the production of IL-37 is impaired in allergic asthmatics, it is likely that IL-37 is involved in asthma pathogenesis. We have previously shown that IL-37 ameliorates experimental asthma via a mechanism that requires the IL-18 recector (R) α and the single Ig IL 1 related receptor (SIGIRR). We a…

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Zitierempfehlung

A Schröder, L Lunding, S Webering, C Vock, D Raedler, B Schaub, H Fehrenbach, M Wegmann (2016) Immunomodulatory role of IL-37 in asthma pathogenesis. Pneumologie (07). https://doi.org/10.1055/s-0036-1584619

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