CareLit · DOI-Nachweis · Pneumologie
α-Linoleic acid enhances the capacity of α1-antitrypsin to inhibit lipopolysaccharide-induced IL-1β in human blood neutrophils
DOI 10.1055/s-0036-1584621
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Autor:innenN Aggarwal, S Wrenger, V Grau, T Welte, S Janciauskiene
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
B Alpha1-antitrypsin (A1AT, SERPINA1), a major circulating inhibitor of neutrophil elastase (NE) and proteinase-3 (PRN3), has been proposed to reduce the processing and release of IL-1β. Since the anti-inflammatory properties of A1AT are influenced by the presence of polyunsaturated fatty acids, we compared effects of fatty acid free (A1AT-0) and α-linoleic acid bound (A1AT-LA) forms of A1AT on lipopolysaccharide (L…
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Zitierempfehlung
N Aggarwal, S Wrenger, V Grau, T Welte, S Janciauskiene (2016) α-Linoleic acid enhances the capacity of α1-antitrypsin to inhibit lipopolysaccharide-induced IL-1β in human blood neutrophils. Pneumologie (07). https://doi.org/10.1055/s-0036-1584621
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