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Chemosensory cholinergic signaling network in the thymic medullary epithelium

A Soultanova, C Cen, K Fleck, G Krasteva-Christ, U Boehm, SM Wienhold, H Müller-Redetzky, M Witzenrath, W Kummer · Pneumologie · Ausgabe 07/2016

DOI 10.1055/s-0036-1584622

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Autor:innenA Soultanova, C Cen, K Fleck, G Krasteva-Christ, U Boehm, SM Wienhold, H Müller-Redetzky, M Witzenrath, W Kummer
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Objective: A subset of medullary epithelial cells in the thymus (mTECs) was previously shown to be cholinergic and express components of bitter taste cascade. In this study we set out to further characterize these cells and elucidate their function. Methods: Immunohistochemistry, real-time RT-PCR and intracellular calcium measurements were conducted on thymi from ChAT- (choline acetyltransferase) and Chrna3-eGFP (ni…

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A Soultanova, C Cen, K Fleck, G Krasteva-Christ, U Boehm, SM Wienhold, H Müller-Redetzky, M Witzenrath, W Kummer (2016) Chemosensory cholinergic signaling network in the thymic medullary epithelium. Pneumologie (07). https://doi.org/10.1055/s-0036-1584622

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