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Potential protective role of secretory leukocyte protease inhibitor (SLPI) in transplanted organs

A Zakrzewicz, S Wilker, S Stumpf, K Petrie, W Padberg, S Janciauskiene, V Grau · Pneumologie · Ausgabe 07/2016

DOI 10.1055/s-0036-1584625

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Autor:innenA Zakrzewicz, S Wilker, S Stumpf, K Petrie, W Padberg, S Janciauskiene, V Grau
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben

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Introduction: During self-limiting acute rejection of experimental allografts, numerous leukocytes, predominantly monocytes, accumulate in the vasculature. They interact with graft endothelia and produce diverse factors able to influence graft outcome. SLPI, in addition to its well-known anti-protease function, was reported to possess potent anti-inflammatory properties, mainly associated with inhibition of nuclear…

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A Zakrzewicz, S Wilker, S Stumpf, K Petrie, W Padberg, S Janciauskiene, V Grau (2016) Potential protective role of secretory leukocyte protease inhibitor (SLPI) in transplanted organs. Pneumologie (07). https://doi.org/10.1055/s-0036-1584625

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