CareLit · DOI-Nachweis · Pneumologie
Modeling of TGFβ pathway dynamics in lung cancer cells
DOI 10.1055/s-0036-1584627
Bibliografische Angaben
Nachweis in CareLit
Autor:innenD Dvornikov, R Engesser, M Schilling, S Depner, J Timmer, U Klingmüller
ZeitschriftPneumologie
Ausgabe07/2016
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Rationale: Transforming growth factor-β (TGFβ)-induced effects are different, even opposite, depending on the cellular type and conditions. TGFβ signaling has been widely acknowledged to contribute to cancerogenesis via enhancing tumor cell metastasis. Numerous attempts to target TGFβ pathway to reduce cancer spread proved to be ineffective. Aim: In the current work we aim to use a systems biology approach to obtain…
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Zitierempfehlung
D Dvornikov, R Engesser, M Schilling, S Depner, J Timmer, U Klingmüller (2016) Modeling of TGFβ pathway dynamics in lung cancer cells. Pneumologie (07). https://doi.org/10.1055/s-0036-1584627
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